A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase

Por Herrera, M. Carmen, Tognetti, Silvia, Riera, Alberto, Zech, Juergen, Clarke, Pippa, Fernández-Cid, Alejandra, Speck, Christian
Publicado no Nucleic Acids Res (2015)

Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function

Por Sun, Jingchuan, Fernandez-Cid, Alejandra, Riera, Alberto, Tognetti, Silvia, Yuan, Zuanning, Stillman, Bruce, Speck, Christian, Li, Huilin
Publicado em 2014

Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation

Por Fatoba, Samuel T., Tognetti, Silvia, Berto, Melissa, Leo, Elisabetta, Mulvey, Claire M., Godovac-Zimmermann, Jasminka, Pommier, Yves, Okorokov, Andrei L.
Publicado em 2013

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA

Por Samel, Stefan A., Fernández-Cid, Alejandra, Sun, Jingchuan, Riera, Alberto, Tognetti, Silvia, Herrera, M. Carmen, Li, Huilin, Speck, Christian
Publicado em 2014

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation

Por Evrin, Cecile, Fernández-Cid, Alejandra, Riera, Alberto, Zech, Juergen, Clarke, Pippa, Herrera, M. Carmen, Tognetti, Silvia, Lurz, Rudi, Speck, Christian
Publicado em 2014

A Clb/Cdk1-mediated regulation of Fkh2 synchronizes CLB expression in the budding yeast cell cycle

Por Linke, Christian, Chasapi, Anastasia, González-Novo, Alberto, Al Sawad, Istabrak, Tognetti, Silvia, Klipp, Edda, Loog, Mart, Krobitsch, Sylvia, Posas, Francesc, Xenarios, Ioannis, Barberis, Matteo
Publicado no NPJ Syst Biol Appl (2017)

Yeast Cip1 is activated by environmental stress to inhibit Cdk1–G1 cyclins via Mcm1 and Msn2/4

Por Chang, Ya-Lan, Tseng, Shun-Fu, Huang, Yu-Ching, Shen, Zih-Jie, Hsu, Pang-Hung, Hsieh, Meng-Hsun, Yang, Chia-Wei, Tognetti, Silvia, Canal, Berta, Subirana, Laia, Wang, Chien-Wei, Chen, Hsiao-Tan, Lin, Chi-Ying, Posas, Francesc, Teng, Shu-Chun
Publicado no Nat Commun (2017)