The ORC/Cdc6/MCM2–7 complex, a new power player for regulated helicase loading

Por Riera, Alberto, Fernández-Cid, Alejandra, Speck, Christian
Publicado em 2013

Yeast importin-β is required for nuclear import of the Mig2 repressor

Por Fernández-Cid, Alejandra, Vega, Montserrat, Herrero, Pilar, Moreno, Fernando
Publicado em 2012

Hexokinase 2 Is an Intracellular Glucose Sensor of Yeast Cells That Maintains the Structure and Activity of Mig1 Protein Repressor Complex

Por Vega, Montserrat, Riera, Alberto, Fernández-Cid, Alejandra, Herrero, Pilar, Moreno, Fernando
Publicado no J Biol Chem (2016)

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase

Por Herrera, M. Carmen, Tognetti, Silvia, Riera, Alberto, Zech, Juergen, Clarke, Pippa, Fernández-Cid, Alejandra, Speck, Christian
Publicado no Nucleic Acids Res (2015)

Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function

Por Sun, Jingchuan, Fernandez-Cid, Alejandra, Riera, Alberto, Tognetti, Silvia, Yuan, Zuanning, Stillman, Bruce, Speck, Christian, Li, Huilin
Publicado em 2014

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA

Por Sun, Jingchuan, Evrin, Cecile, Samel, Stefan, Fernández-Cid, Alejandra, Riera, Alberto, Kawakami, Hironori, Stillman, Bruce, Speck, Christian, Li, Huilin
Publicado em 2013

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA

Por Samel, Stefan A., Fernández-Cid, Alejandra, Sun, Jingchuan, Riera, Alberto, Tognetti, Silvia, Herrera, M. Carmen, Li, Huilin, Speck, Christian
Publicado em 2014

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2–7 hexamer dimerization

Por Evrin, Cecile, Fernández-Cid, Alejandra, Zech, Juergen, Herrera, M. Carmen, Riera, Alberto, Clarke, Pippa, Brill, Shlomo, Lurz, Rudi, Speck, Christian
Publicado em 2013

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation

Por Evrin, Cecile, Fernández-Cid, Alejandra, Riera, Alberto, Zech, Juergen, Clarke, Pippa, Herrera, M. Carmen, Tognetti, Silvia, Lurz, Rudi, Speck, Christian
Publicado em 2014