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MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix

Idiopathic pulmonary fibrosis (IPF) is a lethal and progressive lung disease characterized by persistent (myo)fibroblasts and the relentless accumulation of collagen matrix. Unlike normal lung fibroblasts, IPF lung fibroblasts have suppressed forkhead box O3a (FoxO3a) activity, which allows them to...

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Bibliografiska uppgifter
Huvudupphovsmän: Nho, Richard Seonghun, Im, Jintaek, Ho, Yen-Yi, Hergert, Polla
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200385/
https://ncbi.nlm.nih.gov/pubmed/25172912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00127.2014
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