MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix

Idiopathic pulmonary fibrosis (IPF) is a lethal and progressive lung disease characterized by persistent (myo)fibroblasts and the relentless accumulation of collagen matrix. Unlike normal lung fibroblasts, IPF lung fibroblasts have suppressed forkhead box O3a (FoxO3a) activity, which allows them to...

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Hlavní autoři: Nho, Richard Seonghun, Im, Jintaek, Ho, Yen-Yi, Hergert, Polla
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200385/
https://ncbi.nlm.nih.gov/pubmed/25172912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00127.2014
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