Pathological Alteration of FoxO3a Activity Promotes Idiopathic Pulmonary Fibrosis Fibroblast Proliferation on Type I Collagen Matrix

Idiopathic pulmonary fibrosis (IPF) is a prevalent, progressive, and incurable fibroproliferative lung disease. The phenotype of IPF fibroblasts is characterized by their ability to elude the proliferation-suppressive properties of polymerized type I collagen. The mechanism underlying this pathologi...

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Detalhes bibliográficos
Main Authors: Nho, Richard Seonghun, Hergert, Polla, Kahm, Judith, Jessurun, Jose, Henke, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204034/
https://ncbi.nlm.nih.gov/pubmed/21893017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.020
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