Low α(2)β(1) Integrin Function Enhances the Proliferation of Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis by Activation of the β-Catenin Pathway

Idiopathic pulmonary fibrosis (IPF) is a progressive and incurable fibroproliferative disorder characterized by unrelenting proliferation of fibroblasts and their deposition of collagen within alveoli, resulting in permanently scarred, nonfunctional airspaces. Normally, polymerized collagen suppress...

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Autors principals: Xia, Hong, Seeman, Jeremy, Hong, Jian, Hergert, Polla, Bodem, Vidya, Jessurun, Jose, Smith, Karen, Nho, Richard, Kahm, Judy, Gaillard, Philippe, Henke, Craig
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2012
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388160/
https://ncbi.nlm.nih.gov/pubmed/22642910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.03.034
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