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MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix

Idiopathic pulmonary fibrosis (IPF) is a lethal and progressive lung disease characterized by persistent (myo)fibroblasts and the relentless accumulation of collagen matrix. Unlike normal lung fibroblasts, IPF lung fibroblasts have suppressed forkhead box O3a (FoxO3a) activity, which allows them to...

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Bibliografische gegevens
Hoofdauteurs: Nho, Richard Seonghun, Im, Jintaek, Ho, Yen-Yi, Hergert, Polla
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200385/
https://ncbi.nlm.nih.gov/pubmed/25172912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00127.2014
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