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Effect of Rothia mucilaginosa enzymes on gliadin (gluten) structure, deamidation, and immunogenic epitopes relevant to celiac disease

Rothia mucilaginosa, a natural microbial inhabitant of the oral cavity, cleaves gluten (gliadin) proteins at regions that are resistant to degradation by mammalian enzymes. The aim of this study was to investigate to what extent the R. mucilaginosa cell-associated enzymes abolish gliadin immunogenic...

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Bibliographische Detailangaben
Hauptverfasser: Tian, Na, Wei, Guoxian, Schuppan, Detlef, Helmerhorst, Eva J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200315/
https://ncbi.nlm.nih.gov/pubmed/25147233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00144.2014
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