MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism

Activation of c-MYC is an oncogenic hallmark of many cancers including liver cancer, and is associated with a variety of adverse prognostic characteristics. Despite a causative role during malignant transformation and progression in hepatocarcinogenesis, consequences of c-MYC activation for the biol...

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Bibliographic Details
Main Authors: Akita, Hirofumi, Marquardt, Jens U., Durkin, Marian E., Kitade, Mitsuteru, Seo, Daekwan, Conner, Elizabeth A., Andersen, Jesper B., Factor, Valentina M., Thorgeirsson, Snorri S.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199878/
https://ncbi.nlm.nih.gov/pubmed/25189530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0527
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