Epigenetic Reprogramming Modulates Malignant Properties of Human Liver Cancer

Reversal of DNA hypermethylation and associated gene silencing is an emerging cancer therapy approach. Here we addressed the impact of epigenetic alterations and cellular context on functional and transcriptional reprogramming of HCC cells. Our strategy employed a 3-day treatment of established and...

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Autors principals: Raggi, Chiara, Factor, Valentina M., Seo, Daekwan, Holczbauer, Agnes, Gillen, Matthew C., Marquardt, Jens U., Andersen, Jesper B., Durkin, Marian, Thorgeirsson, Snorri S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043911/
https://ncbi.nlm.nih.gov/pubmed/24449497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27026
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