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Epigenetic Reprogramming Modulates Malignant Properties of Human Liver Cancer

Reversal of DNA hypermethylation and associated gene silencing is an emerging cancer therapy approach. Here we addressed the impact of epigenetic alterations and cellular context on functional and transcriptional reprogramming of HCC cells. Our strategy employed a 3-day treatment of established and...

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Bibliografske podrobnosti
Main Authors: Raggi, Chiara, Factor, Valentina M., Seo, Daekwan, Holczbauer, Agnes, Gillen, Matthew C., Marquardt, Jens U., Andersen, Jesper B., Durkin, Marian, Thorgeirsson, Snorri S.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043911/
https://ncbi.nlm.nih.gov/pubmed/24449497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27026
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