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Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits

BACKGROUND & AIMS: Human hepatocarcinogenesis is as a multi-step process starting from dysplastic lesions to early carcinomas (eHCC) that ultimately progress to HCC (pHCC). However, the sequential molecular alterations driving malignant transformation of the pre-neoplastic lesions are not clearl...

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Detalhes bibliográficos
Main Authors: Marquardt, Jens U., Seo, Daekwan, Andersen, Jesper B., Gillen, Matthew C., Kim, Myoung Soo, Conner, Elizabeth A., Galle, Peter R., Factor, Valentina M., Park, Young Nyun, Thorgeirsson, Snorri S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943679/
https://ncbi.nlm.nih.gov/pubmed/24512821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.10.014
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