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Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
The c-jun N-terminal kinase (JNK) signaling pathway is regulated by JNK-interacting protein-1 (JIP1), which is a scaffolding protein assembling the components of the JNK cascade. Overexpression of JIP1 deactivates the JNK pathway selectively by cytoplasmic retention of JNK and thereby inhibits gene...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2004
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419904/ https://ncbi.nlm.nih.gov/pubmed/15141161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600212 |
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