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Identification of ROCK1 as an Upstream Activator of the JIP-3 to JNK Signaling Axis in Response to UVB Damage

Although apoptosis triggered by ultraviolet B (UVB)-mediated activation of the c-Jun N-terminal kinase (JNK) pathway is mediated by both intrinsic and extrinsic pathways, the mechanism of initiation of JNK activation remains obscure. Here, we report the characterization of the JNK-interacting protei...

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Detalhes bibliográficos
Main Authors: Ongusaha, Pat P., Qi, Hank H., Raj, Lakshmi, Kim, Young-Bum, Aaronson, Stuart A., Davis, Roger J., Shi, Yang, Liao, James K., Lee, Sam W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649725/
https://ncbi.nlm.nih.gov/pubmed/19036714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1161938
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