RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress

The Rho family of GTPases regulates many aspects of cellular behavior through alterations to the actin cytoskeleton [1-6]. The majority of the Rho family proteins function as molecular switches cycling between the active, GTP-bound, and the inactive, GDP-bound, conformations [1-6]. Unlike typical Rh...

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Detalhes bibliográficos
Main Authors: Ongusaha, Pat P., Kim, Hyung-Gu, Boswell, Sarah A., Ridley, Anne J., Der, Channing J., Dotto, G. Paolo, Kim, Young-Bum, Aaronson, Stuart A., Lee, Sam W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779528/
https://ncbi.nlm.nih.gov/pubmed/17174923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2006.10.056
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