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Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling

Aberrations of Notch signaling have been implicated in a variety of human cancers. Oncogenic mutations in NOTCH1 are common in human T-cell leukemia and lymphomas. However, loss-of-function somatic mutations in NOTCH1 arising in solid tumors imply a tumor suppressor function, which highlights the ne...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhu, Zehua, Todorova, Kristina, Lee, Kevin K., Wang, Jun, Kwon, Eunjeong, Kehayov, Ivan, Kim, Hyung-Gu, Kolev, Vihren, Dotto, G. Paolo, Lee, Sam W., Mandinova, Anna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031027/
https://ncbi.nlm.nih.gov/pubmed/24525741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0452
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