Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity

Activation of Notch signaling contributes to glioblastoma multiform (GBM) tumorigenesis. However, the molecular mechanism that promotes the Notch signaling augmentation during GBM genesis remains largely unknown. Identification of new factors that regulate Notch signaling is critical for tumor treat...

詳細記述

保存先:
書誌詳細
出版年:Cancer Med
主要な著者: Liu, Baohui, Lin, Xi, Yang, Xiangsheng, Dong, Huimin, Yue, Xiaojing, Andrade, Kelsey C, Guo, Zhentao, Yang, Jian, Wu, Liquan, Zhu, Xiaonan, Zhang, Shenqi, Tian, Daofeng, Wang, Junmin, Cai, Qiang, Chen, Qizuan, Mao, Shanping, Chen, Qianxue, Chang, Jiang
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Ltd 2015
主題:
Cancer Biology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567025/
https://ncbi.nlm.nih.gov/pubmed/26108681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.484
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