Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity

Activation of Notch signaling contributes to glioblastoma multiform (GBM) tumorigenesis. However, the molecular mechanism that promotes the Notch signaling augmentation during GBM genesis remains largely unknown. Identification of new factors that regulate Notch signaling is critical for tumor treat...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Med
मुख्य लेखकों: Liu, Baohui, Lin, Xi, Yang, Xiangsheng, Dong, Huimin, Yue, Xiaojing, Andrade, Kelsey C, Guo, Zhentao, Yang, Jian, Wu, Liquan, Zhu, Xiaonan, Zhang, Shenqi, Tian, Daofeng, Wang, Junmin, Cai, Qiang, Chen, Qizuan, Mao, Shanping, Chen, Qianxue, Chang, Jiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley & Sons, Ltd 2015
विषय:
Cancer Biology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567025/
https://ncbi.nlm.nih.gov/pubmed/26108681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.484
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