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p53-mediated induction of Cox-2 counteracts p53- or genotoxic stress-induced apoptosis
The identification of transcriptional targets of the tumor suppressor p53 is crucial in understanding mechanisms by which it affects cellular outcomes. Through expression array analysis, we identified cyclooxygenase 2 (Cox-2), whose expression was inducible by wild-type p53 and DNA damage. We also f...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC131088/ https://ncbi.nlm.nih.gov/pubmed/12411481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf591 |
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