Targeting JNK-interacting protein 1 (JIP1) sensitises osteosarcoma to doxorubicin

Osteosarcoma (OS) is the most common primary malignant bone tumour in children and adolescents. Despite aggressive therapy, survival outcomes remain unsatisfactory, especially for patients with metastatic disease or patients with a poor chemotherapy response. Chemoresistance contributes to treatment...

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Detalhes bibliográficos
Main Authors: De Boer, Jantine Posthuma, van Egmond, Pim W., Helder, Marco N., de Menezes, Renée X., Cleton-Jansen, Anne-Marie, Beliën, Jeroen A.M., Verheul, Henk M. W., van Royen, Barend J., Kaspers, Gert-Jan J.L., van Beusechem, Victor W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717953/
https://ncbi.nlm.nih.gov/pubmed/23045411
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