WEE1 inhibition sensitizes osteosarcoma to radiotherapy

BACKGROUND: The use of radiotherapy in osteosarcoma (OS) is controversial due to its radioresistance. OS patients currently treated with radiotherapy generally are inoperable, have painful skeletal metastases, refuse surgery or have undergone an intralesional resection of the primary tumor. After ir...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: PosthumaDeBoer, Jantine, Würdinger, Thomas, Graat, Harm CA, van Beusechem, Victor W, Helder, Marco N, van Royen, Barend J, Kaspers, Gertjan JL
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103478/
https://ncbi.nlm.nih.gov/pubmed/21529352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-156
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