Surface proteomic analysis of osteosarcoma identifies EPHA2 as receptor for targeted drug delivery

BACKGROUND: Osteosarcoma (OS) is the most common bone tumour in children and adolescents. Despite aggressive therapy regimens, treatment outcomes are unsatisfactory. Targeted delivery of drugs can provide higher effective doses at the site of the tumour, ultimately improving the efficacy of existing...

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Detalhes bibliográficos
Main Authors: PosthumaDeBoer, J, Piersma, S R, Pham, T V, van Egmond, P W, Knol, J C, Cleton-Jansen, A M, van Geer, M A, van Beusechem, V W, Kaspers, G J L, van Royen, B J, Jiménez, C R, Helder, M N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798973/
https://ncbi.nlm.nih.gov/pubmed/24064975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.578
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