FERM Domain Interaction Promotes FAK Signaling

From the results of deletion analyses, the FERM domain of FAK has been proposed to inhibit enzymatic activity and repress FAK signaling. We have identified a sequence in the FERM domain that is important for FAK signaling in vivo. Point mutations in this sequence had little effect upon catalytic act...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dunty, Jill M., Gabarra-Niecko, Veronica, King, Michelle L., Ceccarelli, Derek F. J., Eck, Michael J., Schaller, Michael D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Cell Growth and Development
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC419890/
https://ncbi.nlm.nih.gov/pubmed/15169899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5353-5368.2004
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