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FERM Domain Interaction Promotes FAK Signaling

From the results of deletion analyses, the FERM domain of FAK has been proposed to inhibit enzymatic activity and repress FAK signaling. We have identified a sequence in the FERM domain that is important for FAK signaling in vivo. Point mutations in this sequence had little effect upon catalytic act...

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Detalhes bibliográficos
Main Authors: Dunty, Jill M., Gabarra-Niecko, Veronica, King, Michelle L., Ceccarelli, Derek F. J., Eck, Michael J., Schaller, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419890/
https://ncbi.nlm.nih.gov/pubmed/15169899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5353-5368.2004
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