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Phospholipid binding to the FAK catalytic domain impacts function
Focal adhesion kinase is an essential nonreceptor tyrosine kinase that plays an important role in development, in homeostasis and in the progression of human disease. Multiple stimuli activate FAK, which requires a change in structure from an autoinhibited to activated conformation. In the autoinhib...
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| Veröffentlicht in: | PLoS One |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319746/ https://ncbi.nlm.nih.gov/pubmed/28222177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172136 |
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