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Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function

Chitin is an important structural component of numerous fungal pathogens and parasitic nematodes. The human macrophage chitotriosidase (HCHT) is a chitinase that hydrolyses glycosidic bonds between the N-acetyl-D-glucosamine units of this biopolymer. HCHT belongs to the Glycoside Hydrolase (GH) supe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Crasson, Oscar, Courtade, Gaston, Léonard, Raphaël R., Aachmann, Finn Lillelund, Legrand, François, Parente, Raffaella, Baurain, Denis, Galleni, Moreno, Sørlie, Morten, Vandevenne, Marylène
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459812/
https://ncbi.nlm.nih.gov/pubmed/28584264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02382-z
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