Targeted Inactivation of Serum Response Factor in the Developing Heart Results in Myocardial Defects and Embryonic Lethality

Serum response factor (SRF) is at the confluence of multiple signaling pathways controlling the transcription of immediate-early response genes and muscle-specific genes. There are active SRF target sequences in more than 50 genes expressed in the three muscle lineages including normal and diseased...

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Main Authors: Parlakian, Ara, Tuil, David, Hamard, Ghislaine, Tavernier, Geneviève, Hentzen, Daniele, Concordet, Jean-Paul, Paulin, Denise, Li, Zhenlin, Daegelen, Dominique
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Cell Growth and Development
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC419888/
https://ncbi.nlm.nih.gov/pubmed/15169892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5281-5289.2004
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