Inactivation of the Sema5a Gene Results in Embryonic Lethality and Defective Remodeling of the Cranial Vascular System

The semaphorins are a large family of proteins involved in the patterning of both the vascular and the nervous systems. In order to analyze the function of the membrane-bound semaphorin 5A (Sema5A), we generated mice homozygous for a null mutation in the Sema5a gene. Homozygous null mutants die betw...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fiore, Roberto, Rahim, Belquis, Christoffels, Vincent M., Moorman, Antoon F. M., Püschel, Andreas W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061610/
https://ncbi.nlm.nih.gov/pubmed/15743826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2310-2319.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados