Complete Loss of Ndel1 Results in Neuronal Migration Defects and Early Embryonic Lethality

Regulation of cytoplasmic dynein and microtubule dynamics is crucial for both mitotic cell division and neuronal migration. NDEL1 was identified as a protein interacting with LIS1, the protein product of a gene mutated in the lissencephaly. To elucidate NDEL1 function in vivo, we generated null and...

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Detalhes bibliográficos
Main Authors: Sasaki, Shinji, Mori, Daisuke, Toyo-oka, Kazuhito, Chen, Amy, Garrett-Beal, Lisa, Muramatsu, Masami, Miyagawa, Shuji, Hiraiwa, Noriko, Yoshiki, Atsushi, Wynshaw-Boris, Anthony, Hirotsune, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190282/
https://ncbi.nlm.nih.gov/pubmed/16107726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7812-7827.2005
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