Complete Loss of Ndel1 Results in Neuronal Migration Defects and Early Embryonic Lethality

Regulation of cytoplasmic dynein and microtubule dynamics is crucial for both mitotic cell division and neuronal migration. NDEL1 was identified as a protein interacting with LIS1, the protein product of a gene mutated in the lissencephaly. To elucidate NDEL1 function in vivo, we generated null and...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sasaki, Shinji, Mori, Daisuke, Toyo-oka, Kazuhito, Chen, Amy, Garrett-Beal, Lisa, Muramatsu, Masami, Miyagawa, Shuji, Hiraiwa, Noriko, Yoshiki, Atsushi, Wynshaw-Boris, Anthony, Hirotsune, Shinji
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2005
נושאים:
Mammalian Genetic Models with Minimal or Complex Phenotypes
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190282/
https://ncbi.nlm.nih.gov/pubmed/16107726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7812-7827.2005
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