Complete Loss of Ndel1 Results in Neuronal Migration Defects and Early Embryonic Lethality

Regulation of cytoplasmic dynein and microtubule dynamics is crucial for both mitotic cell division and neuronal migration. NDEL1 was identified as a protein interacting with LIS1, the protein product of a gene mutated in the lissencephaly. To elucidate NDEL1 function in vivo, we generated null and...

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Bibliografische gegevens
Hoofdauteurs: Sasaki, Shinji, Mori, Daisuke, Toyo-oka, Kazuhito, Chen, Amy, Garrett-Beal, Lisa, Muramatsu, Masami, Miyagawa, Shuji, Hiraiwa, Noriko, Yoshiki, Atsushi, Wynshaw-Boris, Anthony, Hirotsune, Shinji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190282/
https://ncbi.nlm.nih.gov/pubmed/16107726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7812-7827.2005
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