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Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects

Autotaxin (ATX) is a secretory protein, which converts lysophospholipids to lysophosphatidic acid (LPA), and is essential for embryonic vascular formation. ATX is abundantly detected in various biological fluids and its level is elevated in some pathophysiological conditions. However, the roles of e...

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Publié dans:PLoS One
Auteurs principaux: Yukiura, Hiroshi, Kano, Kuniyuki, Kise, Ryoji, Inoue, Asuka, Aoki, Junken
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438000/
https://ncbi.nlm.nih.gov/pubmed/25992708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126734
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