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Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects

Autotaxin (ATX) is a secretory protein, which converts lysophospholipids to lysophosphatidic acid (LPA), and is essential for embryonic vascular formation. ATX is abundantly detected in various biological fluids and its level is elevated in some pathophysiological conditions. However, the roles of e...

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Pubblicato in:PLoS One
Autori principali: Yukiura, Hiroshi, Kano, Kuniyuki, Kise, Ryoji, Inoue, Asuka, Aoki, Junken
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438000/
https://ncbi.nlm.nih.gov/pubmed/25992708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126734
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