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Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects

Autotaxin (ATX) is a secretory protein, which converts lysophospholipids to lysophosphatidic acid (LPA), and is essential for embryonic vascular formation. ATX is abundantly detected in various biological fluids and its level is elevated in some pathophysiological conditions. However, the roles of e...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Yukiura, Hiroshi, Kano, Kuniyuki, Kise, Ryoji, Inoue, Asuka, Aoki, Junken
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438000/
https://ncbi.nlm.nih.gov/pubmed/25992708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126734
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