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Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects

Autotaxin (ATX) is a secretory protein, which converts lysophospholipids to lysophosphatidic acid (LPA), and is essential for embryonic vascular formation. ATX is abundantly detected in various biological fluids and its level is elevated in some pathophysiological conditions. However, the roles of e...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Yukiura, Hiroshi, Kano, Kuniyuki, Kise, Ryoji, Inoue, Asuka, Aoki, Junken
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438000/
https://ncbi.nlm.nih.gov/pubmed/25992708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126734
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