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Disruption of the Arnt gene in endothelial cells causes hepatic vascular defects and partial embryonic lethality
Vascular endothelial cells (ECs) play a critical role in angiogenesis and organogenesis, especially in embryonic liver development. Hypoxia inducible transcription factors (Hif) are a key trigger for hypoxic signals, a primary stimulus for angiogenesis. Aryl hydrocarbon receptor nuclear translocator...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1559728/ https://ncbi.nlm.nih.gov/pubmed/16941684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21284 |
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