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Disruption of the Arnt gene in endothelial cells causes hepatic vascular defects and partial embryonic lethality

Vascular endothelial cells (ECs) play a critical role in angiogenesis and organogenesis, especially in embryonic liver development. Hypoxia inducible transcription factors (Hif) are a key trigger for hypoxic signals, a primary stimulus for angiogenesis. Aryl hydrocarbon receptor nuclear translocator...

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Bibliografske podrobnosti
Main Authors: Yim, Sun Hee, Shah, Yatrik, Tomita, Shuhei, Morris, H. Douglas, Gavrilova, Oksana, Lambert, Gilles, Ward, Jerrold M., Gonzalez, Frank J.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559728/
https://ncbi.nlm.nih.gov/pubmed/16941684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21284
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