Mir-290–295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects

Mir-290 through mir-295 (mir-290–295) is a mammalian-specific microRNA (miRNA) cluster that, in mice, is expressed specifically in early embryos and embryonic germ cells. Here, we show that mir-290–295 plays important roles in embryonic development as indicated by the partially penetrant lethality o...

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Detalhes bibliográficos
Main Authors: Medeiros, Lea A., Dennis, Lucas M., Gill, Mark E., Houbaviy, Hristo, Markoulaki, Styliani, Fu, Dongdong, White, Amy C., Kirak, Oktay, Sharp, Phillip A., Page, David C., Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161528/
https://ncbi.nlm.nih.gov/pubmed/21844366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111241108
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