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ATX-LPA(1) axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation
The lipid mediator lysophosphatidic acid (LPA) signals via six distinct G protein-coupled receptors to mediate both unique and overlapping biological effects, including cell migration, proliferation and survival. LPA is produced extracellularly by autotaxin (ATX), a secreted lysophospholipase D, fro...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804234/ https://ncbi.nlm.nih.gov/pubmed/27005960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23433 |
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