SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

Manganese (Mn) is an essential metal, but elevated cellular levels are toxic and may lead to the development of an irreversible parkinsonian-like syndrome that has no treatment. Mn-induced parkinsonism generally occurs as a result of exposure to elevated Mn levels in occupational or environmental se...

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Xehetasun bibliografikoak
Egile Nagusiak: Leyva-Illades, Dinorah, Chen, Pan, Zogzas, Charles E., Hutchens, Steven, Mercado, Jonathan M., Swaim, Caleb D., Morrisett, Richard A., Bowman, Aaron B., Aschner, Michael, Mukhopadhyay, Somshuvra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198546/
https://ncbi.nlm.nih.gov/pubmed/25319704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2329-14.2014
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