SLC30A10: A novel manganese transporter

Homozygous mutations in SLC30A10 cause familial parkinsonism associated with manganese (Mn) retention. We recently identified SLC30A10 to be a cell surface-localized Mn efflux transporter and demonstrated that parkinsonism-causing mutations block its intracellular trafficking and efflux function. In...

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Detalhes bibliográficos
Publicado no:Worm
Main Authors: Chen, Pan, Bowman, Aaron B, Mukhopadhyay, Somshuvra, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588552/
https://ncbi.nlm.nih.gov/pubmed/26430566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21624054.2015.1042648
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