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Apolipoprotein E4 Produced in GABAergic Interneurons Causes Learning and Memory Deficits in Mice
Apolipoprotein (apo) E4 is expressed in many types of brain cells, is associated with age-dependent decline of learning and memory in humans, and is the major genetic risk factor for AD. To determine whether the detrimental effects of apoE4 depend on its cellular sources, we generated human apoE kno...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Neuroscience
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198545/ https://ncbi.nlm.nih.gov/pubmed/25319703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2281-14.2014 |
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