Serum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome

High level microsatellite instability (MSI-H) occurs in about 15% of colorectal cancer (CRCs), either as sporadic cancers or in the context of hereditary non-polyposis cancer (HNPCC) or Lynch syndrome. In MSI-H CRC, mismatch repair deficiency leads to insertion/deletion mutations at coding microsate...

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Hauptverfasser: Reuschenbach, Miriam, Kloor, Matthias, Morak, Monika, Wentzensen, Nicolas, Germann, Anja, Garbe, Yvette, Tariverdian, Mirjam, Findeisen, Peter, Neumaier, Michael, Holinski-Feder, Elke, Doeberitz, Magnus von Knebel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198384/
https://ncbi.nlm.nih.gov/pubmed/19957108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-009-9307-z
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