High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability

High-level microsatellite instability (MSI-H) in colorectal cancer accounts for about 12% of colorectal cancers and is typically associated with a dense infiltration with cytotoxic CD8-positive lymphocytes. The role of regulatory T cells that may interfere with the host's antitumoural immune re...

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Detalhes bibliográficos
Main Authors: Michel, S, Benner, A, Tariverdian, M, Wentzensen, N, Hoefler, P, Pommerencke, T, Grabe, N, von Knebel Doeberitz, M, Kloor, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600708/
https://ncbi.nlm.nih.gov/pubmed/18985040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604756
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