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High endothelial venules are associated with microsatellite instability, hereditary background and immune evasion in colorectal cancer
BACKGROUND: Microsatellite-unstable (MSI) tumours show a high load of mutational neoantigens, as a consequence of DNA mismatch repair deficiency. Consequently, MSI tumours commonly present with dense immune infiltration and develop immune evasion mechanisms. Whether improved lymphocyte recruitment c...
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| Publicado en: | Br J Cancer |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738093/ https://ncbi.nlm.nih.gov/pubmed/31358939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0514-6 |
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