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Complex pattern of immune evasion in MSI colorectal cancer
Mismatch repair (MMR)-deficient cancers accumulate multiple insertion/deletion mutations at coding microsatellites (cMS), which give rise to frameshift peptide neoantigens. The high mutational neoantigen load of MMR-deficient cancers is reflected by pronounced anti-tumoral immune responses of the ho...
Shranjeno v:
| izdano v: | Oncoimmunology |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993484/ https://ncbi.nlm.nih.gov/pubmed/29900056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1445453 |
| Oznake: |
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