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Coding Microsatellite Frameshift Mutations Accumulate in Atherosclerotic Carotid Artery Lesions: Evaluation of 26 Cases and Literature Review

Somatic DNA alterations are known to occur in atherosclerotic carotid artery lesions; however, their significance is unknown. The accumulation of microsatellite mutations in coding DNA regions may reflect a deficiency of the DNA mismatch repair (MMR) system. Alternatively, accumulation of these codi...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Kurz, Carolin, Hakimi, Maani, Kloor, Matthias, Grond-Ginsbach, Caspar, Gross-Weissmann, Marie-Luise, Böckler, Dittmar, von Knebel Doeberitz, Magnus, Dihlmann, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607617/
https://ncbi.nlm.nih.gov/pubmed/26070012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00258
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