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Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms

BACKGROUND: Phenotypic transformation of vascular smooth muscle cells is a key element in vascular remodeling and aortic aneurysm growth. Previously, deletion of several inflammasome components decreased formation of aortic aneurysm (AA) in the Angiotensin II (AngII) -induced mouse model. We hypothe...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Wortmann, Markus, Arshad, Muhammad, Hakimi, Maani, Böckler, Dittmar, Dihlmann, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493160/
https://ncbi.nlm.nih.gov/pubmed/32933486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-020-00212-z
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