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Triazole Containing Novobiocin and Biphenyl Amides as Hsp90 C-Terminal Inhibitors
Hsp90 C-terminal inhibitors are advantageous for the development of new cancer chemotherapeutics due to their ability to segregate client protein degradation from induction of the prosurvival heat shock response, which is a major detriment associated with Hsp90 N-terminal inhibitors under clinical i...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198308/ https://ncbi.nlm.nih.gov/pubmed/25328661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00102H |
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