KISS1R Signals Independently of Gα(q/11) and Triggers LH Secretion via the β-Arrestin Pathway in the Male Mouse

Hypothalamic GnRH is the master regulator of the neuroendocrine reproductive axis, and its secretion is regulated by many factors. Among these is kisspeptin (Kp), a potent trigger of GnRH secretion. Kp signals via the Kp receptor (KISS1R), a Gα(q/11)-coupled 7-transmembrane–spanning receptor. Until...

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Hlavní autoři: Ahow, Maryse, Min, Le, Pampillo, Macarena, Nash, Connor, Wen, Junping, Soltis, Kathleen, Carroll, Rona S., Glidewell-Kenney, Christine A., Mellon, Pamela L., Bhattacharya, Moshmi, Tobet, Stuart A., Kaiser, Ursula B., Babwah, Andy V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
Témata:
Neuroendocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197989/
https://ncbi.nlm.nih.gov/pubmed/25147978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1304
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