Regulation of GPR54 Signaling by GRK2 and β-Arrestin

Kisspeptin and its receptor, GPR54, are major regulators of the hypothalamic-pituitary-gonadal axis as well as regulators of human placentation and tumor metastases. GPR54 is a G(q/11)-coupled G protein-coupled receptor (GPCR), and activation by kisspeptin stimulates phosphatidy linositol 4, 5-bipho...

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Bibliographic Details
Published in:Mol Endocrinol
Main Authors: Pampillo, Macarena, Camuso, Natasha, Taylor, Jay E., Szereszewski, Jacob M., Ahow, Maryse R., Zajac, Mateusz, Millar, Robert P., Bhattacharya, Moshmi, Babwah, Andy V.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2009
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419131/
https://ncbi.nlm.nih.gov/pubmed/19846537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0013
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