Single-Cell Analyses Reveal That KISS1R-Expressing Cells Undergo Sustained Kisspeptin-Induced Signaling That Is Dependent upon An Influx of Extracellular Ca(2+)

The kisspeptin receptor (KISS1R) is a Gα(q/11)-coupled seven-transmembrane receptor activated by a group of peptides referred to as kisspeptins (Kps). The Kp/KISS1R signaling system is a powerful regulator of GnRH secretion, and inactivating mutations in this system are associated with hypogonadotro...

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Main Authors: Babwah, Andy V., Pampillo, Macarena, Min, Le, Kaiser, Ursula B., Bhattacharya, Moshmi
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2012
Teme:
General Endocrinology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512071/
https://ncbi.nlm.nih.gov/pubmed/23070548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1747
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