Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

Telomere length homeostasis is essential for the long-term survival of stem cells, and its set point determines the proliferative capacity of differentiated cell lineages by restricting the reservoir of telomeric repeats. Knockdown and overexpression studies in human tumor cells showed that the shel...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sexton, Alec N., Regalado, Samuel G., Lai, Christine S., Cost, Gregory J., O’Neil, Colleen M., Urnov, Fyodor D., Gregory, Philip D., Jaenisch, Rudolf, Collins, Kathleen, Hockemeyer, Dirk
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2014
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197946/
https://ncbi.nlm.nih.gov/pubmed/25128433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.246819.114
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन