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Specificity Requirements for Human Telomere Protein Interaction with Telomerase Holoenzyme

Human telomeres are maintained by the enzyme telomerase, which uses a template within its integral RNA subunit (hTR) and telomerase reverse transcriptase protein (TERT) to accomplish the synthesis of single-stranded DNA repeats. Many questions remain unresolved about the cellular regulation of telom...

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Autori principali: Sexton, Alec N., Youmans, Daniel T., Collins, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464550/
https://ncbi.nlm.nih.gov/pubmed/22893708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394767
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