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Specificity Requirements for Human Telomere Protein Interaction with Telomerase Holoenzyme
Human telomeres are maintained by the enzyme telomerase, which uses a template within its integral RNA subunit (hTR) and telomerase reverse transcriptase protein (TERT) to accomplish the synthesis of single-stranded DNA repeats. Many questions remain unresolved about the cellular regulation of telom...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464550/ https://ncbi.nlm.nih.gov/pubmed/22893708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394767 |
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