DNA Mapping Using Microfluidic Stretching and Single-Molecule Detection of Fluorescent Site-Specific Tags

We have developed a rapid molecular mapping technology—Direct Linear Analysis (DLA)—on the basis of the analysis of individual DNA molecules bound with sequence-specific fluorescent tags. The apparatus includes a microfluidic device for stretching DNA molecules in elongational flow that is coupled t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chan, Eugene Y., Goncalves, Nuno M., Haeusler, Rebecca A., Hatch, Amie J., Larson, Jonathan W., Maletta, Anthony M., Yantz, Gregory R., Carstea, Eugene D., Fuchs, Martin, Wong, Gordon G., Gullans, Steven R., Gilmanshin, Rudolf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2004
Aiheet:
Methods
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC419792/
https://ncbi.nlm.nih.gov/pubmed/15173119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1635204
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