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Selective inhibition of calcineurin-NFAT signaling by blocking protein–protein interaction with small organic molecules
Transient or reversible protein–protein interactions are commonly used to ensure efficient targeting of signaling enzymes to their cellular substrates. These interactions include direct binding to substrate, interaction with an accessory or scaffold protein, and positioning at subcellular locations...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419644/ https://ncbi.nlm.nih.gov/pubmed/15131267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401835101 |
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